ABSTRACT
Objective To investigate and analyze the clinical efficacy of psychological intervention combined with three amino alcohol in the treatment of postpartum hemorrhage in pregnancy and its influence on the quality of life. Methods In our hospital 64 cases of high-risk pregnancy postpartum hemorrhage patients as the research object, the control group of carboprost ammonia butyl alcohol three treatment, the experimental group on the basis of psychological intervention, communicate actively with the patient, do psychological counseling work, the right to assess the psychological status of patients, increase confidence in treatment and treatment patient compliance. Results The quality of life score of the control group was (60.30 ± 9.20), significantly lower than that of the experimental group, and the score was (76.88 ± 10.90) points, with statistical difference (P<0.05). The amount of postpartum 2H bleeding and the volume of postpartum 24h in the experimental group were (117.56 ± 40.23) mL and (269.08 ±96.57) mL, significantly less than that in the control group, and there was a statistical difference (P<0.05). In the experimental group, the postpartum hemorrhage was 9 cases (28.13%), and the rate of postpartum hemorrhage in the control group was 15.63%, which was statistically significant (P<0.05). Conclusion The clinical efficacy of psychological intervention combined with three amino alcohol in the treatment of postpartum hemorrhage of pregnancy is ideal, can significantly reduce the amount of bleeding and improve the quality of life of patients.
ABSTRACT
Objective To investigate and analyze the clinical efficacy of psychological intervention combined with three amino alcohol in the treatment of postpartum hemorrhage in pregnancy and its influence on the quality of life. Methods In our hospital 64 cases of high-risk pregnancy postpartum hemorrhage patients as the research object, the control group of carboprost ammonia butyl alcohol three treatment, the experimental group on the basis of psychological intervention, communicate actively with the patient, do psychological counseling work, the right to assess the psychological status of patients, increase confidence in treatment and treatment patient compliance. Results The quality of life score of the control group was (60.30 ± 9.20), significantly lower than that of the experimental group, and the score was (76.88 ± 10.90) points, with statistical difference (P<0.05). The amount of postpartum 2H bleeding and the volume of postpartum 24h in the experimental group were (117.56 ± 40.23) mL and (269.08 ±96.57) mL, significantly less than that in the control group, and there was a statistical difference (P<0.05). In the experimental group, the postpartum hemorrhage was 9 cases (28.13%), and the rate of postpartum hemorrhage in the control group was 15.63%, which was statistically significant (P<0.05). Conclusion The clinical efficacy of psychological intervention combined with three amino alcohol in the treatment of postpartum hemorrhage of pregnancy is ideal, can significantly reduce the amount of bleeding and improve the quality of life of patients.
ABSTRACT
<p><b>OBJECTIVE</b>Infants less than 35 weeks of gestational age are susceptible to peri-/intraventricular hemorrhage (PIVH). This may be due in part to low concentrations of vitamin K-dependent coagulation factors. This study was conducted to determine the umbilical cord blood activities of vitamin K-dependent coagulation factors II, VII, IX and X in premature infants to understand whether preterm infants have absence status of these factors the changes of theses factors' activities in premature infants' umbilical blood after vitamin K(1) was given to mothers antenatally and the preventing effectiveness of PIVH after maternal antenatal supplement of vitamin K(1).</p><p><b>METHODS</b>Pregnant women in preterm labor at less than 35 weeks of gestational age were randomly selected to receive antenatal vitamin K(1) intramuscular or intravenous injections 10 mg per day for 2 to 7 days (vitamin K(1) group), or no vitamin K(1) treatment (control group). Dexamethone was antenatally given to both groups of pregnant women routinely. Vitamin K(1) group had 44 infants and the control group had 133 infants. During the same period, thirty full-term neonates' cord blood samples were obtained to determine theses factors to compare with those from the premature infants. The cranial ultrasound was performed by a same physician to understand whether the neonates were complicated with PIVH and its severity.</p><p><b>RESULTS</b>The levels of vitamin K-dependent coagulation factors in umbilical blood in control group were significantly lower than those in full-term infants' cord blood (P < 0.05). However, in vitamin K(1) group, supplement of vitamin K(1) antenatally could significantly increase activities of factors II, VII and X in preterm infants' cord blood (P < 0.05). The total occurrence rates of PIVH in vitamin K(1) group and control group were 31.8% and 52.6%, respectively, (P = 0.017), and the frequency of severe PIVH in vitamin K(1) group and control group was 2.3% and 12.0%, respectively (P = 0.057).</p><p><b>CONCLUSION</b>Preterm infants have absence status of vitamin K-dependent coagulation factors. Administration of vitamin K(1) to pregnant women at less than 35 weeks of gestational age resulted in significantly improved activities of vitamin K-dependent coagulation factors II, VII, and X, and a significantly decreased frequency of PIVH and less severe hemorrhage in preterm infants.</p>